DPCstruct | MC20359

Metacluster Properties and Pfam Annotations

Number of structural domains154
Mean domain length (aa)170 ± 44 aa
Standard deviation of domain lengths43.84
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score83.27
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)23.41
Pfam Score94.64
Assigned Pfam label(s) PF05190- PF05188- PF05192

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H3JC05 422-643 None
A0A4S4MS98 280-463 None
H2KQV6 653-820 None
A0A821LQI0 1-123 None
K2RXG6 11-139 None
A0A4U0URA5 365-524 None
A0A287IRS4 178-369 None
D8SDK2 670-846 None
A0A7M3Q697 292-514 None
D8LY06 236-361 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.