DPCstruct | MC20359

Metacluster Properties and Pfam Annotations

Number of structural domains154
Mean domain length (aa)170 ± 44 aa
Standard deviation of domain lengths43.84
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score83.27
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)23.41
Pfam Score94.64
Assigned Pfam label(s) PF05190- PF05188- PF05192

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y7X6E2 2-130 SSFMFIDAVTIRNLELVGNLKDSTKNDTLLAILENNLTPMGTRFLRDALLRPLIDTTEINKRLDAVGTLVYDYTLRGNLRAKLKSIQ…
A0A3S4VRK6 2-115 LDAATRRNLELTQNLAGGTENTLAAVLDKCVTPMGSRLLKRWIHQPIRDLEKLKKRQDIIDTLQKEQRIELLQPLLQNVGDMERILA…
A0A229Y375 906-1193 None
A0A2V2VN48 170-345 None
A0A0V0QKW8 230-319 None
A0A2I9CJD1 297-415 None
A0A7S3ZRR1 249-424 None
A0A453E8P3 55-234 None
A0A7X7XE34 261-423 None
A0A0A8WP32 266-410 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.