DPCstruct | MC20318

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)196 ± 12 aa
Standard deviation of domain lengths11.86
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score80.56
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)23.03
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A165PRB3 31-235 TTYARFSADPGRLMEWRDHLELDELSTSTSAPPDVRYARILPYLVKAKDELVRAHGWKDAQHRVDLDTMAFAIEKTVRGASYALAFP…
W4JX74 8-206 SRYAYVKFESNNCPWWEDYTGLDALTFKQLELAYARAREFILEQVEVLVKSHGWSPQSGISTAELFSLARGDRTLWLPTAFSAFFDT…
A0A0C3C311 19-195 None
A0A0C9VM21 3-192 None
A0A4Z0A2P4 5-201 None
A0A146IGN9 3-209 None
G4TCB3 3-218 None
A0A4V3XG38 56-238 None
A0A0C3F0H7 511-693 None
A0A5C3MY03 2-184 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.