DPCstruct | MC20314

Metacluster Properties and Pfam Annotations

Number of structural domains36
Mean domain length (aa)470 ± 102 aa
Standard deviation of domain lengths102.04
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score82.68
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)15.39
Pfam Score65.00
Assigned Pfam label(s) PF02026- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A353E5T8 106-580 EFIGLYLLYDDQLQNLAKNIKLRGDEYFKGNMAQKAYIFCRATSGKLNGGTAFEYNSRYGVETILVDAAQLAIKTMMAKRETHPANY…
R5AQK3 3-358 TRKPFPTPHIVCFGEADALAETLPLYANSHQSGAYVSNPSKRTRISVVTDDTDFIDDFMFIRKELIENSFRRVVDLRGEIPQVRLYK…
A0A1F5VKU3 278-765 None
A0A1Y4NA72 517-997 None
A0A7C4GAV5 89-594 None
A0A518DVH5 35-629 None
A0A7W5ZQ77 362-906 None
A0A0M1J9C1 83-648 None
A0A1G4WXA2 8-371 None
A0A1Q6KQC1 287-886 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.