DPCstruct | MC20310

Metacluster Properties and Pfam Annotations

Number of structural domains150
Mean domain length (aa)220 ± 47 aa
Standard deviation of domain lengths47.38
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.26
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)17.18
Pfam Score96.88
Assigned Pfam label(s) PF02602- CL0304

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D3SMG8 2-235 KKRAALCGSRKKEEFLKMMAETDIEAYVEEVVTIEYLPAEEVAKKLEEVLSLKPSHFLFTTGEGVQRLFQVAEEYGVLPHLLQLLKN…
A0A1U7S6W5 1-217 MKVLLLKDPKERDSGPDPYIQELGSYGFEATLIPVLSFEFVSLQSLFEKLSHPECYGGLIFTSPRAVEAVKLCLKENSKNEAWTKSL…
A0A8A5ZFZ4 1-161 None
A0A6L5C411 177-388 None
A0A1F2UZA8 6-209 None
A0A7J0EKA1 42-295 None
A0A0D6R6F5 2-161 None
A0A7W2CC15 13-231 None
A0A2E3K4A8 10-227 None
A0A838YX42 2-222 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.