DPCstruct | MC20270

Metacluster Properties and Pfam Annotations

Number of structural domains53
Mean domain length (aa)101 ± 14 aa
Standard deviation of domain lengths13.83
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score86.31
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)29.74
Pfam Score40.00
Assigned Pfam label(s) CL0689- CL0022- CL0159

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2E3VYY1 123-218 IPFVSTWRVGDAGYGDGDLTVTLPLRSGFNYNFTVDWGDGKTDEVTAHNDSDIDHLYDSGGDYTITISGLVEAWYFNNAGDKDKIIS…
A0A0B8PKU5 129-217 SVVEPRPFITTWKIEADNDEVIIPTRSSRYTYDYNIDWGDGTIEENQTGDVRHTYTLPGTYTISINGVFPNLTTLGGSEKLPMLSLE…
A0A661IQR1 262-347 None
A0A2E3W278 122-209 None
A0A2T6B932 10-121 None
A0A0F9CBA7 11-116 None
A0A3G2LAY5 1-107 None
A0A6G2KV53 4-103 None
A0A6N7EXC4 59-154 None
A0A2R7RJ73 148-244 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.