DPCstruct | MC20250

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)113 ± 7 aa
Standard deviation of domain lengths7.49
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score91.12
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)28.02
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0H2QVI2 1-99 MGLTAWLASDDTGTSSRYMAAILSGQFNAPNHYPLDPADLGRCIRLLEAAPELESELHKMKSCSPQWRSVVDNWNKWKDLYEAGKGG…
A0A5C7KG21 129-237 LPTSVQKWLATGNRGRSSEAMCRAIFGVPVDGDGSGWRHPLDADDFRRCLGFLKAVPEARKQLVLIADKSPTWASLVEHWGELEALY…
A0A0F9S9D3 3-109 None
F2LSD4 17-129 None
A0A0B1RU46 9-122 None
A0A0E3BB61 45-160 None
D3SGL3 65-186 None
A0A1U9LJF2 26-151 None
A0A522KZZ2 75-205 None
A0A1J5IEI7 6-123 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.