DPCstruct | MC2024

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)108 ± 9 aa
Standard deviation of domain lengths9.28
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score87.54
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)25.42
Pfam Score100.00
Assigned Pfam label(s) PF20212

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
B6B950 3-109 ILDQNSIDIIQVDQAGQTTRLIIIDHLEWIGRKPDDEHLWQLQEKVNDYLKYIESGQLDADYPDQMGNRVVIQVYGKFDRPPAAVAF…
D4FS83 189-290 KPTELDAIGIVDSHLELLLVDPVGWEEEIEVVHLEILQEKMNNYIHFLESKQYVARYGDKFDKKVIHIKLQYSPSDNGLAFLAAVQK…
A0A1F9HAF2 9-112 None
B9XKD3 134-237 None
A0A2V9H7U4 2-120 None
A0A0S8F5N7 2-107 None
A0A7Z7I5J9 5-107 None
A0A8B6N140 183-295 None
I8I5J7 272-386 None
J3D2B4 29-134 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.