DPCstruct | MC20200

Metacluster Properties and Pfam Annotations

Number of structural domains600
Mean domain length (aa)194 ± 41 aa
Standard deviation of domain lengths41.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score83.99
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.40
Mean intra-cluster sequence similarity (%)11.53
Pfam Score95.59
Assigned Pfam label(s) CL0023- CL0273- PF02179- PF05011- CL0632

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R4QHU2 279-492 None
A0A351EYM0 12-214 None
A0A6A4ZCF0 3-194 None
U2WJL8 1-135 None
A0A4E0QW32 3-161 None
A0A537PGE6 7-140 None
W4UHP3 21-153 None
A0A4Q7M3G2 31-204 None
A0A4Y3TXW1 4-168 None
A0A7R9K2I9 226-413 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.