DPCstruct | MC20200

Metacluster Properties and Pfam Annotations

Number of structural domains600
Mean domain length (aa)194 ± 41 aa
Standard deviation of domain lengths41.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score83.99
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.40
Mean intra-cluster sequence similarity (%)11.53
Pfam Score95.59
Assigned Pfam label(s) CL0023- CL0273- PF02179- PF05011- CL0632

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453BRR4 2-137 None
A0A1I1CE81 4-143 None
A0A061NSY5 7-189 None
A0A1U7MR13 108-310 None
A0A1Y2GI08 134-337 None
H3HDN6 475-637 None
A0A4V3FRM7 166-387 None
A0A367KKI7 170-414 None
A0A5A8ECJ1 16-227 None
A0A4S8JH58 422-617 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.