DPCstruct | MC20200

Metacluster Properties and Pfam Annotations

Number of structural domains600
Mean domain length (aa)194 ± 41 aa
Standard deviation of domain lengths41.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score83.99
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.40
Mean intra-cluster sequence similarity (%)11.53
Pfam Score95.59
Assigned Pfam label(s) CL0023- CL0273- PF02179- PF05011- CL0632

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A498KJ94 2-199 EVEVKLRLLDAAAHRQVTTLLAPFLVATHRQENFFFDGSKAELSARLAVLRLRFSDRSPLCAVTLKARAVLVDGISRVEEDEEELDH…
A0A0N8W9Z7 7-207 SEVECKYKINSLANYHQVLEYLKNSYSLQTCQKLTNYLLDTTGFKLRERKLILRMRISPEQNLISLKGKNQIIDGLNFARRIEIEFS…
A0A4S4DMR0 121-357 None
A0A3L7WEH2 34-246 None
A0A3Q0IIN0 58-261 None
A0A3N5F6R3 13-197 None
A0A811LJS0 19-205 None
A0A1E5B919 7-149 None
A0A5S6Q6K7 13-188 None
A0A317VWN9 1-157 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.