DPCstruct | MC2020

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)119 ± 16 aa
Standard deviation of domain lengths15.96
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score83.35
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)28.20
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A668AAB0 2-130 SNDRCWRCDKERGTLIHMFYECDVVHSLWGAVIQCINNALKVKLRENPALCILGILQRKIGLSQQLRLWVKLALATGNRVILRHWKS…
A0A803T586 11-136 NKNNNEKCWRGCQEIGTYMHMWWDCKHLTSYWKVVQTECNKILKSKFELKPEIFLLGLSDPKENLDANKDKLFTYFITAARIIIAKH…
A0A7J5XFD4 117-221 None
A0A670JHA9 805-941 None
A0A0G2JUT3 314-439 None
A0A2H6N757 60-200 None
A0A3B5PRH3 698-826 None
H3B1Z1 228-340 None
A0A452TRQ8 15-123 None
A0A671TUA1 2-132 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.