DPCstruct | MC20195

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)221 ± 15 aa
Standard deviation of domain lengths15.25
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score72.48
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)54.19
Pfam Score100.00
Assigned Pfam label(s) PF08074

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183EHB6 92-293 PVKKESESTKVIRSKGPRPSFKFNIADGGFTELHTLWLNEEKAAVPGNEFEIWHRRHDYWLLVGIITYGYGRYQDLQNDPRFAIINE…
A0A0M3KB69 91-305 KETTPDSNSNSRMETDKEEDKMETDEGAPKGVVSKEEDRKNRAPRPSFKFNIADGGFTELHTLWLNEEKAAVPGNEYEIWHRRHDFW…
A0A493TZQ9 570-777 None
A0A0C2MIY8 276-503 None
A0A817F8U5 415-624 None
A0A2R7WMA9 210-455 None
A0A0C2CR21 777-993 None
A0A4C1YMQ3 38-280 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.