DPCstruct | MC20172

Metacluster Properties and Pfam Annotations

Number of structural domains92
Mean domain length (aa)157 ± 25 aa
Standard deviation of domain lengths24.64
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score71.32
Mean fraction of residues predicted as intrinsically disordered0.56
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)27.90
Pfam Score87.32
Assigned Pfam label(s) CL0123- PF14774- CL0105- CL0023

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2T6DA88 21-121 LINLQDFLEHVQLMRSDDFYEKVAHTSPQLARFFEERNPRLLRRIESIILSMTIFERRNPRVLKLSLSRRARVAVGSGVPMSHIDDL…
A0A536WQ51 16-156 DVDEAKKFAEKLKKGKGFDLEDFKQQIGQMRKMGGISSMIDKLPAQFAPAAQSAQMDEKQLRRVEGIINSMTPAERMRPEILKASRK…
A0A7S2LAC0 1-160 None
A0A0D9XP62 908-1049 None
A0A099NPK1 3-158 None
A0A3D0IBW7 4-136 None
A0A812NMD9 297-448 None
M1VD16 1-186 None
L1LGH5 6-206 None
A0A836QUR2 125-278 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.