DPCstruct | MC20163

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)101 ± 11 aa
Standard deviation of domain lengths10.98
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score81.33
Mean fraction of residues predicted as intrinsically disordered0.76
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)44.02
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7V8ISD5 7-112 SITRAAIRLVSKTRQSNLALDEGLTNWEGEFLDGLEERLQKYGSAFNDPDLGATCGALSLRQGLKLKQIKRKAQPKKTVKALLPKTG…
A0A840I2A4 27-106 EKKARERSARNAQRKIARLRKTLAENGEITDFEDEFAGSVAERLDKYGAAFADPGLGRPGDALSSAQKRVVASMNRKVKE
A0A840A8E6 7-100 None
A0A7W6A478 25-125 None
A0A258HPN4 14-115 None
A3UH51 3-116 None
A0A3B0RY73 9-118 None
A0A2S8W898 1-90 None
E8RQB1 32-123 None
A0A2D8FLL4 11-104 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.