DPCstruct | MC2015

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)122 ± 12 aa
Standard deviation of domain lengths11.95
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score80.28
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)23.31
Pfam Score93.29
Assigned Pfam label(s) CL0172- PF21109

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2U9BB22 685-803 SQNGLHEETLSAEHAVCFIFTSLGSAEPYLSALSNYLKVSIKPDDPQDPHAHDVEKEQWYLSKQVFDTLREKAKLFSDFAEANKENK…
A0A6A5EG53 131-263 MEGIKIVPNQSALDRQVFARGVEDALCFVFTSVERGDTYLDVMAGYLDYPKLGSTNEDPWYYSNEVLNKMRKKAKAFQHFANAQKSN…
A0A7M5U144 1-91 None
A0A7M5VGG4 414-537 None
A0A7R8X5Z1 217-334 None
A0A7R8ZZF3 176-292 None
A0A1X7SFC2 4-123 None
A0A498MEQ0 343-464 None
A0A6G0HX93 136-258 None
A0A0F8CZ11 383-501 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.