DPCstruct | MC20139

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)171 ± 24 aa
Standard deviation of domain lengths23.88
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score68.77
Mean fraction of residues predicted as intrinsically disordered0.38
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)32.99
Pfam Score100.00
Assigned Pfam label(s) PF12579

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A2Y169 26-184 RHNPGISVNWTPDEQLTLEDLLAKYASDSTIVRYAKIAMELKDKTVRDVALRCRWMTKENGKQRKEDHSSARKIKDKKFIELHLGVT…
A0A5D2R1S8 4-181 ATEWSTEEQYILKDGLEKYKEEPNIMKYIKIAAVLPDKTVRDVALRCRWLQIKRRKPEELNAGKKVNNRKDKQVESSSKMNTPTALP…
A0A251SJY5 7-167 None
A0A1Z5RPI9 14-209 None
F6GX50 1-154 None
A0A453DEI8 2-164 None
A0A6P5FPY8 298-481 None
M4CKM9 2-206 None
A0A6N2B1Z2 12-143 None
A0A3L6PYA5 45-262 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.