DPCstruct | MC20113

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)101 ± 15 aa
Standard deviation of domain lengths14.67
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score88.23
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)31.63
Pfam Score100.00
Assigned Pfam label(s) PF14198

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R7KYH3 12-100 GKYAIQRKNVLKDHFPAAYQRMQMDGTLEEHLAYTQESVSNYVDICAERYKQTEEYKQAEAADPMEAMRLLNMTVLEAEEAAYRSWI…
A0A174FJP4 1-111 MNVQYEQQGNYLIPCIRTKEQEEIHLGVLANRHRQYLKQNHKVRYYNLLTRERLYDYLDGVECQAEDLFEQTVKSLAEKEQVTEKLK…
A0A847P9N3 62-177 None
A0A7X3MM76 91-204 None
A0A6M4WEG5 8-106 None
U2CUY8 1-91 None
R9LMU3 10-90 None
A0A415E520 38-129 None
A8RX52 1-101 None
E7GGA6 3-79 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.