DPCstruct | MC20110

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)78 ± 9 aa
Standard deviation of domain lengths8.82
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score83.94
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)21.18
Pfam Score100.00
Assigned Pfam label(s) PF10115

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0S3PR36 20-92 SEPEDYKGFVLRAAPFDAEGQFQTAGSISKEVGGETKTHEFIRADRHASYEEAVSFALMKARQIVDEQGDRVF
A0A1F5V0K2 2-70 DKNRISYNGYIIEANTHQLETKKWTLDITIYKNYGNKVVAKPFYSNNTFENKEDAINNCYIFGSNIIDG
A0A4V6P5C5 1-70 None
A0A535BFL0 3-71 None
A0A534S6P5 1-70 None
A0A244DPY4 1-66 None
A0A2V7BRE9 2-95 None
A0A561XIN0 20-86 None
A0A1W1I0M8 3-81 None
H4F0E5 4-104 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.