DPCstruct | MC20105

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)148 ± 17 aa
Standard deviation of domain lengths17.24
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score81.74
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)24.06
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A094B0V6 436-613 MSKGPRLCPDERLRSRLYEPLVLLHVLDRNGEQRISRCPSEDLVAPQLQQLRELRRDFLDKLAYICDHVKGGDTVTAIALEAHPSGI…
A0A1V6PI53 15-156 KRVGRPRLDPYQRLLGRFYEQLFLLNALGQTRGNHKTSSFELDAARARRRRFLQNLCFVCDFRKGGSTCTAIGLEELDTRYNFFVAS…
A0A4V3HW37 266-404 None
A0A175W4P0 177-303 None
A0A420MIK2 6-143 None
A0A2H4SIU9 201-362 None
A0A2H2Z9A1 16-185 None
A0A4Q4YTJ6 1-152 None
A0A094AYR8 5-157 None
A0A0A2V643 3-150 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.