DPCstruct | MC2010

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)217 ± 20 aa
Standard deviation of domain lengths19.80
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score87.93
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)47.27
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R9IVB9 326-543 LDGPRPPQKDILAIRAYILLFLKQLIMIGNGVKDDELQSILNYLTTMHEDENLHDVLQMLISLISEHPASMVPAFDVKQGVRSIFKL…
A0A0M3KHH5 2-185 ALTTRLLAERPAVMVPAFDRNKGLAVVFKLLNSTNELIRVPALKIFGFFLCRSTLKRKNDSVGNLNLFTLLTDRLLLNASYLSLATY…
A0A0V0XHR6 670-870 None
H0XPV2 570-801 None
A0A3Q0IZU0 1-253 None
A0A6A5FRB7 113-332 None
A0A817QFF4 42-271 None
W2TJQ2 93-327 None
A0A336M010 74-295 None
A0A336KVB2 3-190 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.