DPCstruct | MC20077

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)99 ± 15 aa
Standard deviation of domain lengths14.98
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score77.76
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)39.69
Pfam Score100.00
Assigned Pfam label(s) PF15795

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D7FIX6 5-79 RKTFIDPPVLRKPLAFVLLVINVFVPGLGTVIAGFLTCKLKSIFTGILQLVTTSLVVGWVWSVMWGWELWTLARR
A0A0K0ENC7 29-121 RHGVLRKAIPCMTMPNAIFCCISNFIIPGLGTLLSAFAIPTGSNYESDQTMIWAFMTNILTAFLQLITAPLIVGFIWSMIWGIIFIQ…
A0A7I8VSI4 119-222 None
A0A814BRN7 588-686 None
E2B3U4 154-254 None
A0A195CP38 1006-1127 None
A0A6J3C5S1 1-91 None
A0A2A6CTB7 85-176 None
A0A077ZXW3 5-87 None
P16537 94-187 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.