DPCstruct | MC20015

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)131 ± 11 aa
Standard deviation of domain lengths11.33
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score88.97
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)27.30
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A417GPN5 5-147 VRPATKTEQMYCYTQSDQIMGQTGCIGHLRADMGDSGDQFFHDWTSHCERLLTPEFDDEFNQLINQLREDDGFLKSRAAVSAYCYRQ…
V2XTU1 12-138 CPFPEVFQDTERVEGSFIDVPRRKIGHIRADHDNYRWWSTVWPCHSELVTPAITMEIDQVYDALTANDALADFETLVQFCHAHPEAR…
A0A1Q6KM35 13-141 None
A0A1Y3RUU5 8-147 None
V9HIN8 31-158 None
A0A4R2MEG0 96-228 None
A0A373B6C2 59-182 None
A0A1Y4LGQ3 13-149 None
A0A2N5ICE1 2-111 None
A0A4R1QXV2 13-156 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.