DPCstruct | MC20012

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)379 ± 34 aa
Standard deviation of domain lengths33.54
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score78.68
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)17.01
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q4JXJ4 1-332 MSRINALNVALVLAASVLGLLSITLNANPVPTQDNAISNSLALYYSLGPILGFIGAKEMARFRSFFKSRGSVQDVFKVWLRSLALPL…
A0A423UG39 2-377 PALFAGIASSVLCRQFDAANVLVGGVASRGSSRIWAYHLRRVVSLVLLGYVLGLIPLFIRLTATATWGSPDILALLDGCAVMCFLAT…
A0A7W0A5A9 1-435 None
A0A1G9XA81 4-379 None
A0A433FAT6 26-445 None
A0A7M1R1G0 17-423 None
A0A4R9AMN2 68-479 None
A0A4Y3MZY4 6-389 None
A0A7X0P449 19-388 None
A0A438MPT0 19-388 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.