DPCstruct | MC2001

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)88 ± 13 aa
Standard deviation of domain lengths12.66
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score94.88
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)39.44
Pfam Score100.00
Assigned Pfam label(s) CL0046

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0J9XQZ5 279-353 IRKLSNRLYQKTGLTPNDVQVIELHDCFAPNELISYEALGLCPIGKGGDIVDKGDNTYGGKWVINPSGGLISKGH
A0A2D6T869 146-226 LPEPLEIPGAAAAARQAYQRAGIGPGDVDFAEIYDCFTISALLQIEDLGFCGKGEAAAFIRERGITIDGGLPVNTHGGLLS
A0A2E1Y0N4 310-388 None
A0A6G3VUW6 1-110 None
A0A7W1QDE6 5-87 None
A0A813QBL0 247-347 None
A0A2A2K1N2 277-379 None
A0A2S8BJC1 589-686 None
L5K376 531-605 None
F8F1C3 178-249 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.