DPCstruct | MC20008

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)251 ± 29 aa
Standard deviation of domain lengths29.42
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score92.95
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)22.38
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C0VE00 41-308 IFQIILQIYGWEEGWNLLVRMGANARIFDQSGNVRDAVINREIAVGTTIDFYGYTAQWLNPEFCRYVFPADGTIVNADPIALLTTSQ…
A0A1V5M7L1 21-278 AEGWRTALNLLKRIGANCRYFTDSASKVPLDVAQGNAAAGMCIDFYGRFQSETVEREEGSKRMRYFTPTGGSSFSADPVGILRGAPD…
A0A7J2LBD8 28-267 None
A0A7T9EHF3 313-608 None
A0A2R7PSV4 10-249 None
A0A3S4LN77 3-215 None
A0A662I617 1-215 None
A0A662G653 3-228 None
A0A3C1AXZ4 202-460 None
A0A5J4E2G9 1-216 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.