DPCstruct | MC20

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)269 ± 32 aa
Standard deviation of domain lengths31.51
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score85.90
Mean fraction of residues predicted as intrinsically disordered0.86
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)36.17
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I2SNP8 2-249 QRHAKVAEAEAKEKEAEAALTQAKADNKMTQQEHDDLAAKNDAVTAAKADAAKAVEGLPAGDAKDGLNGRLAKVDGIDVPAVDENGN…
A0A0A2YJF0 9-310 SIARWYCISRRRWKQWRQGIIPYWGGVESTQITAAKDAVKAAEEAYQKAKNLLDKAKEDNQITAEEELALKEANKAIEDAKTKAEEA…
A0A1B3JFD3 150-410 None
A0A8A6QPV1 647-903 None
A0A376Y320 267-502 None
A0A833PCA5 2-236 None
A0A376ZSY6 562-851 None
A0A8B5JM22 290-548 None
A0A8B4R870 1-309 None
A0A240BSQ1 625-907 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.