DPCstruct | MC19970

Metacluster Properties and Pfam Annotations

Number of structural domains112
Mean domain length (aa)122 ± 19 aa
Standard deviation of domain lengths18.87
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score85.65
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)39.36
Pfam Score98.36
Assigned Pfam label(s) CL0603- CL0118- CL0530

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A446N6W1 2-83 HNLRQYKVPLQRYVAMMDLQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRRPQGLYVSLRDKGKVIDVLRNWP
A0A1C3EHD1 2-120 SDPAFNKGTAFSIQERDRFGLHGLLPPHIESLDEQVQRVYEAYQRKDDDLERHIYLRALQDTNEVLFYRLLLEHIEEMLPIVYTPVV…
A0A7H4SJG6 9-144 None
A0A817PZA6 1-107 None
A0A817QS50 368-475 None
A0A6D2HEF4 435-578 None
A0A6D2JFL9 1-119 None
A0A5N3WKJ4 27-138 None
A0A453E6P2 76-194 None
B5IJQ0 289-415 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.