DPCstruct | MC19965

Metacluster Properties and Pfam Annotations

Number of structural domains43
Mean domain length (aa)229 ± 53 aa
Standard deviation of domain lengths53.35
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score75.85
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)18.97
Pfam Score97.92
Assigned Pfam label(s) PF10173- CL0113

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2C5XM48 2-253 RLFVLPVSTKRSLLYAQRFNATTTATNASLSDRLTRRANAMWASWEAKDGGWQKHLVLYGNKLLRQIPMEEWSLKSVPPLSSQLQKL…
A0A0U2ZU66 2-157 KDRGLCWIAEKIAEQRLLWRLRNETRLILHHPDDMTVDEANGIARAELQREADRHMKWIVIDGLLFVGSGLFFLVPGPNLIAYYFGF…
A0A1V2LP21 33-218 None
A7EWT3 42-266 None
A0A0G2IGQ2 14-322 None
A0A178BJB1 50-450 None
B8NZV0 7-247 None
A4RZS1 4-240 None
A0A7C9DS14 1-181 None
A0A287TLK6 10-214 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.