DPCstruct | MC1995

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)93 ± 5 aa
Standard deviation of domain lengths5.44
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score92.73
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.97
Mean intra-cluster local Distance Difference Test score0.95
Mean intra-cluster sequence similarity (%)60.94
Pfam Score81.94
Assigned Pfam label(s) PF14711- CL0344

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A377D117 191-284 RYLGVLLYDADAIERAASTENEKDLYQRQLEVFLDPNDPKVIEQAIKDGIPLSVIEAAQQSPVYKMAMEWKLALPLHPEYRTLPMVW…
X7Z478 2-88 LYDADRVLDAAATPDLQDLYEAQLGVFLDPNDPHVVAEAARQGIPHDWIQAAQRSPVYELAVRHKVALPLHPEYRTLPMVWYIPPLS
A0A447U377 60-146 None
A0A0C2MKV8 250-344 None
F9EIH6 269-360 None
A0A377E5C6 16-104 None
A0A7Y5RTR5 54-146 None
A0A376TGF4 53-145 None
A0A377BGU8 52-146 None
A0A0H2KH28 46-140 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.