DPCstruct | MC19939

Metacluster Properties and Pfam Annotations

Number of structural domains6671
Mean domain length (aa)157 ± 45 aa
Standard deviation of domain lengths44.96
Length coefficient of variation0.29
Mean AlphaFold2 pLDDT confidence score82.29
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)13.19
Pfam Score55.01
Assigned Pfam label(s) CL0681- PF16963- PF05231- PF06580- CL0263

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q5YEH8 5-124 EQLELLHRRMVEEVQDYAIILLDLDGTILSWNKGAQQIKGYTPDEILGQNFRLFYLPRHREEGLPEALLAQATKEGRARHIGIRLRK…
A0A291LVK2 8-137 DGVQMTIDRLPVALTVADPSQPDCPLVAVNGRFQEMTGYAPADVIGRNCRFLQDGCDGSDNEAAREAIRTALSRARGVEVVLRNRTR…
A0A654HJM4 4-150 None
A0A1I4QPH4 325-546 None
F4PPD4 43-272 None
A0A6P1TL32 209-376 None
A0A2U8GGE9 166-381 None
H0UQR1 49-301 None
A0A4Q8U0A6 19-176 None
A0A401FIS4 10-138 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.