DPCstruct | MC19908

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)128 ± 12 aa
Standard deviation of domain lengths11.71
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score82.42
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)34.73
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R3XRA4 84-214 MVNRLFVVSYEIDYVHRVSVGVTADSPKAAQQIAEQAFNDGTIWDDTAAMPLLSDEYHEVEDESLVWESVTVEQLPEPDYSVRQLKK…
A0A291IQ78 51-193 EVLTEENPSPAYAVTYTLDYTHRVVVGIVAESADGAQAVAEAAFDDGTIWDDTPEMPLLFDDFEEVDGETLRWQVEAVDVWPKADAS…
F2LRM7 26-171 None
A0A2S5Q9V9 1-126 None
A0A1G0KUK0 80-188 None
H8GPN2 2-115 None
A0A3M1EG88 2-119 None
A0A2S5CII9 5-127 None
A0A4R1BDT9 4-139 None
A0A658AB53 2-146 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.