DPCstruct | MC19890

Metacluster Properties and Pfam Annotations

Number of structural domains189
Mean domain length (aa)125 ± 20 aa
Standard deviation of domain lengths20.14
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score82.73
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)18.29
Pfam Score93.37
Assigned Pfam label(s) PF02470- PF02405- PF11887

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A379W8B3 238-345 None
A0A2V2S4I0 110-250 None
A0A1W9WPJ9 8-147 None
A0A819E3G2 25-139 None
A0A0P0ZB71 26-150 None
A0A7Y2KX90 367-476 None
C6WN65 72-199 None
A0A6U9RP80 7-134 None
A0A453RS05 2-125 None
A0A7M2ZLU8 16-157 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.