DPCstruct | MC19846

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)372 ± 52 aa
Standard deviation of domain lengths52.31
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score86.45
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)27.76
Pfam Score90.00
Assigned Pfam label(s) PF12500- CL0533

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W8V3B0 105-448 LEVKVDAAALPAATLFGFAERRNPKRAFLFVSKVLGRLVPTRPSIMAASFESLVSEIPADLPGPVLVIGVAEAAVGLGAGVHRAYSA…
A0A5Q2N1R9 3-400 KRLMEALDGEQAYVTPKGTFVLPSSHLFIGFAETATALGQAVFSCFEQNALYWHTTREKINELPDLFDFEEEHCHAPEHRLYAVKAS…
J7ISK8 33-462 None
A0A1G8UIL2 20-455 None
A0A1Q9HX51 7-353 None
A0A521G388 14-284 None
A0A8A9EH45 1-276 None
A0A286CF37 44-463 None
A0A7J0CME7 27-431 None
A0A660NDS0 334-714 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.