DPCstruct | MC19746

Metacluster Properties and Pfam Annotations

Number of structural domains184
Mean domain length (aa)87 ± 15 aa
Standard deviation of domain lengths14.78
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score78.76
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)23.25
Pfam Score98.94
Assigned Pfam label(s) CL0010- CL0644- CL0730- CL0173

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H9H490 2-64 GADTPTSCCFSYISRHIPQNFVADYFETSSQCSKPGVIFLTKRGRQVCADPSEDWVQKYVSDL
A0A3Q3M453 2-87 LLVILLLKRVIFFFKEPMKSCCTQYHESPIPFKALQHYTVQDEKQNCNIKAIIFTTKKNRLVCANPDREWVQYAIGERNIRESKGP
A0A218VD49 237-318 None
E1BSX8 148-231 None
A0A3Q4MWP1 6-78 None
A0A6J2REX0 6-103 None
A0A6J3GG38 100-173 None
A0A7J7FGE6 1-72 None
A0A498NGC2 9-100 None
O35903 1-113 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.