DPCstruct | MC19675

Metacluster Properties and Pfam Annotations

Number of structural domains425
Mean domain length (aa)86 ± 13 aa
Standard deviation of domain lengths12.85
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.94
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)18.42
Pfam Score96.04
Assigned Pfam label(s) CL0014- CL0639- CL0654

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A399TL73 29-105 None
A0A4U2EAD2 207-285 None
A0A4Q3AUJ9 4-80 None
A0A2R6DNN9 68-150 None
A0A3N9U770 157-254 None
U5VYV2 130-214 None
F9EMF5 57-151 None
A0A1U9KB44 69-158 None
A0A142Y937 4-81 None
A0A224XCI5 11-95 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.