DPCstruct | MC19675

Metacluster Properties and Pfam Annotations

Number of structural domains425
Mean domain length (aa)86 ± 13 aa
Standard deviation of domain lengths12.85
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.94
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)18.42
Pfam Score96.04
Assigned Pfam label(s) CL0014- CL0639- CL0654

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5R9NXX2 241-325 None
H0HJ55 4-82 None
A0A2M8RTC4 118-213 None
D4C547 336-421 None
A0A497BVU1 86-169 None
K1X8T0 370-449 None
A0A502JBG5 2-64 None
A0A1Y5FD32 73-146 None
A0A7L4YCC2 303-397 None
T0RM11 72-164 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.