DPCstruct | MC19675

Metacluster Properties and Pfam Annotations

Number of structural domains425
Mean domain length (aa)86 ± 13 aa
Standard deviation of domain lengths12.85
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.94
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)18.42
Pfam Score96.04
Assigned Pfam label(s) CL0014- CL0639- CL0654

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1J4UR86 4-70 TRKKVERALAEGVLIDITYESAKRVVTERGVLPECVWEEDGREYCLGFCTLRNAERTFRLDRIKEIS
A0A7H0VIT7 129-216 PSRNKKEAQLLKIQKAIVEYQILHLKYLDSAGKWSERDVEPLGLYFTVESWVMVAHCRLRQEEREFRVDRIQEILDKDEHFALRPFAL
A0A259SXV8 1-64 None
A0A0V8GEW7 8-85 None
A0A251ZT25 87-169 None
A0A1Y2S783 90-184 None
A0A1H4DAI3 141-233 None
A0A7V2XLN4 7-88 None
A0A6L5XQR8 131-252 None
A0A4Z1CST1 111-195 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.