DPCstruct | MC19642

Metacluster Properties and Pfam Annotations

Number of structural domains71
Mean domain length (aa)97 ± 17 aa
Standard deviation of domain lengths17.12
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score90.24
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)34.31
Pfam Score100.00
Assigned Pfam label(s) PF20979

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5F9C1Z3 163-247 GFWHSPECEFVRYCIAKSQERVEGKVQVSVFKGQVYILGRESPLSLYNEELVSMNVQGDYEPIDATGFININSLRLKEYHRLQSK
A0A7U8U615 260-353 TDQRWAELVYDGLWYSPLKAALEAFVAKTQEHVSGEVRLVLHGGHIAVNGRRSAESLYDFNLATYDEGDSFDQSAARGFVYVHGLSS…
A0A2B4S7F2 297-409 None
A0A1G3YLS4 2-63 None
A0A2L2X9B5 2-67 None
A0A7Y5EW81 71-162 None
A0A667I390 487-595 None
A0A5N5ICM9 374-467 None
A0A556TYL1 81-186 None
A0A5J5CR08 415-526 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.