DPCstruct | MC19593

Metacluster Properties and Pfam Annotations

Number of structural domains167
Mean domain length (aa)400 ± 98 aa
Standard deviation of domain lengths98.06
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score66.62
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.36
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)17.99
Pfam Score0.00
Assigned Pfam label(s) CL0361- CL0163- CL0523

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W9HMU4 1-172 MGASSLSEGFSEKELVGLIDIICPYCLHALPAQQVFDDREWQNHVINDLDAYICLFEDCDQPDVLYSHSDEWLCHLQQHRRFWRCAS…
Q7SBG3 40-420 ASVKDVLGKFMLWAGPQGALRKPESESSLDSRLANSPDLQDCIDFELAVMFEALEDHRLDIDYVRRKHPKLGDGVQSSRMGRAIAMR…
A0A4Z0YKC1 51-508 None
A0A4Z0YTH5 49-474 None
A0A1L9TZ86 7-429 None
A0A3N4IEG3 172-700 None
A0A3N4IEH1 54-576 None
A0A084RL79 17-447 None
K2SGB7 1-623 None
A0A395H8J5 2-447 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.