DPCstruct | MC19588

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)122 ± 11 aa
Standard deviation of domain lengths11.49
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score81.21
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)32.53
Pfam Score75.00
Assigned Pfam label(s) CL0007- CL0010

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4X2KVI2 1-127 VYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKA…
A0A1S3GY41 1-104 VYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKA…
A0A818Z1I3 11-141 None
A0A665U6T9 74-186 None
A0A0N4T5K1 60-166 None
A0A7R9A4C9 54-176 None
A0A818QIF9 185-315 None
A7SM36 61-201 None
E4WU63 34-152 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.