DPCstruct | MC19575

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)567 ± 100 aa
Standard deviation of domain lengths99.85
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score91.83
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)33.70
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A243V4M1 1-428 MVDFSSVNVSSNPGVATLINPQYIASVKHNKGYQSVSFGDGQNSYHIVDRNEHSSSDLHTPRLDKLVTEVAPATVTSSSTADILNPS…
A0A2A6D4T2 3-539 LLIMSLMISFNIANASTVSSLIDYQVFRDFAENKGIFKPGTENITIYKKDGSVAGILNKAPMPDFKSVDRSGVATLVNPQYVVSVKH…
A0A378NFS1 38-695 None
A0A378NJC0 18-610 None
A0A378F342 1-580 None
I6DI19 1-416 None
A0A246W9C2 38-501 None
A0A5V1IPY0 24-662 None
A0A2X5PFE9 2-557 None
A0A656BN70 30-641 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.