DPCstruct | MC19534

Metacluster Properties and Pfam Annotations

Number of structural domains4365
Mean domain length (aa)200 ± 48 aa
Standard deviation of domain lengths47.65
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score81.87
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)12.74
Pfam Score37.73
Assigned Pfam label(s) CL0681- PF16963- CL0020- PF05524- PF06580

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H1D3C2 23-281 None
A0A3A5AM92 128-314 None
A0A512DG11 8-291 None
A0A3M7FLA8 13-189 None
F5UCV9 9-220 None
G3I8X7 85-282 None
A0A244DE39 2-148 None
A0A424MUN7 22-317 None
A0A060QMA6 526-709 None
A0A1G9IHY0 4-213 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.