DPCstruct | MC19534

Metacluster Properties and Pfam Annotations

Number of structural domains4365
Mean domain length (aa)200 ± 48 aa
Standard deviation of domain lengths47.65
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score81.87
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)12.74
Pfam Score37.73
Assigned Pfam label(s) CL0681- PF16963- CL0020- PF05524- PF06580

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R5Q2X8 265-400 None
A0A2E8J9J0 8-218 None
V4NEJ6 17-203 None
A0A378W1R9 16-133 None
A0A140HL49 8-175 None
A0A7V2AC39 62-347 None
A0A6P0VSG9 12-199 None
A0A257FT23 511-713 None
C6BZF4 345-510 None
C6BZF5 386-645 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.