DPCstruct | MC19534

Metacluster Properties and Pfam Annotations

Number of structural domains4365
Mean domain length (aa)200 ± 48 aa
Standard deviation of domain lengths47.65
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score81.87
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)12.74
Pfam Score37.73
Assigned Pfam label(s) CL0681- PF16963- CL0020- PF05524- PF06580

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R3UNY0 37-171 GQKLSDETMAKHPELLSVTLHGNPPGLTETYTMFAGSFPERVGNPDDPDDIDVIKKGITIVDPRWKRVKDNPKKVVILMPMRDAQGE…
K2CYQ6 6-185 QQLRLLERITETISYNLDLDEVLMQVVALVSETMKADSCLIYLTQDHHLILKASKIPHPKMINKVALRYGEGITGWVAEHRKIVAVS…
A0A7W1E6R8 6-189 None
A0A7W1BML3 27-194 None
A0A2G4GY88 45-234 None
A0A7W0L4N0 112-281 None
A0A7W0GAM4 122-323 None
U1QXS5 111-285 None
A0A2R6KPB8 591-811 None
A0A2G6ZGF8 258-468 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.