DPCstruct | MC19500

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)522 ± 33 aa
Standard deviation of domain lengths32.53
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score75.06
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)43.02
Pfam Score90.30
Assigned Pfam label(s) CL0063- CL0123- CL0196- CL0487- PF18441

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453AQP6 115-625 NFPTSYHPLVGHLSVTLRRTGDLLGKLPISAIVACDVKVHILCKIIDPKAEFDPLLVLSMIYNAAKQSLGVSVSSRNLWIQSQRPYS…
A0A7C9CGR4 2-512 LIAVSEEELWIRRREPYPCDLMESLIHQQSPMTSEACIEAVCIPFSLDKDVTSMSLNLGSKGYYLDIIAQDLGVVDASKVLISRVIG…
A0A811NRH3 42-479 None
A0A6J0ME23 106-646 None
A0A7J7LA33 3-545 None
A0A453BLF7 1-543 None
A0A834ZNA1 298-837 None
A0A6P4Q590 2-487 None
A0A6A3D1T8 130-635 None
A0A6J0PSE0 119-691 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.