DPCstruct | MC19454

Metacluster Properties and Pfam Annotations

Number of structural domains38
Mean domain length (aa)92 ± 7 aa
Standard deviation of domain lengths7.33
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score82.94
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)35.81
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A146HE19 58-145 ALFRIPRPWEMQRPKFTTDDIDELVDFFEQVDTIIELGGISDEQERKQLLTSYLPVNKRILWRSLDTYQRSCSLKEFVTEIRRMYPEL
A0A2G8SJ48 1-101 MAQAAKQTMPVRGEKTCPKFDEADPTSLHRYFDDLEALFVRHSMPDADQDDWKVRKELAVRYPPAAVEYGWKSLPEFTEVTKNYTDF…
B8PMQ8 5-95 None
A0A2H3BMW0 2-86 None
A0A0C3AII1 1-81 None
B0DE29 15-104 None
A0A2H3CG60 1-84 None
A0A2H3CL68 5-97 None
A0A2H3CPQ6 3-90 None
A0A4S4LZF1 113-180 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.