DPCstruct | MC19446

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)103 ± 6 aa
Standard deviation of domain lengths6.34
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score87.87
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)23.87
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A364Y687 4-113 RTYTPVWHKYRPAILKMMIESTTEPQSYQLSNHEFKALNPKQKGGYAFSLQVSGGKAVSGLKNSVVAQDLWEILQLSPKAIEMIATS…
A0A1M7RIJ0 1-102 MGSQHLYTDIWRKEFQDILALTEFFPSSGKQLSAADFEAVGNRKRYAFRLEIADGMVVNNIDGSAVARDLAEVLLASEQVRSISTGK…
A0A1W2G4W6 10-112 None
A0A3D6ER10 4-87 None
A0A7J0AQ37 63-165 None
A0A1M3DKB9 204-312 None
A0A1M7N0M2 31-138 None
N0BGD2 4-104 None
A0A1N6KA91 2-103 None
B2A7U9 3-106 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.