DPCstruct | MC19443

Metacluster Properties and Pfam Annotations

Number of structural domains87
Mean domain length (aa)141 ± 19 aa
Standard deviation of domain lengths18.95
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score86.95
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)12.64
Pfam Score46.97
Assigned Pfam label(s) PF10898- PF11163- PF20541

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3N7DP77 43-213 LTSEEYESKWEIVLKSIFINRNTALPNLVFSKNFDLLVLEGGCLFVEEDFKKLQECILNVGDEFLFIIENDFGGRLKEPTFRMRFPS…
A0A7Y9CSU5 6-148 VILSDNKTAIIRKKIEEELYKTFKSGSSTYWFPLKDIKDNIPVIAFNSDYWDDDYKMQSLLNLMKCHNIKKAYTLQENSNVYVYDDY…
A0A7U6Y455 2-180 None
A0A5C4T5C7 113-262 None
A0A518HMH5 36-189 None
A0A1Y6BKP5 5-149 None
A0A849WTH8 259-374 None
B9XID1 3-150 None
A0A3D1PFL4 2-162 None
A0A1G6I7V1 28-167 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.