DPCstruct | MC19439

Metacluster Properties and Pfam Annotations

Number of structural domains251
Mean domain length (aa)143 ± 22 aa
Standard deviation of domain lengths22.31
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score77.51
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)23.72
Pfam Score99.63
Assigned Pfam label(s) CL0229- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S1HZ82 73-196 VEQCIRCIEDTTSVSKAEEEEELKMHLRDVGLSSIRVSLQCPVTQIRMAVPGKGMYCMHIQPFDLRQFLLRNLLEHDRLQGNCPECG…
A0A443SGJ0 30-162 ENTWDIIHKKKAKFETEIEDTKWIVSLVCPISKTRMRMPCRSSKCDHIQCFDREVFLSIAKKQNHWKCPLCLKPLATSDLRIDTLLE…
M1W4L5 544-704 None
A0A0D2HWV7 423-565 None
A0A2H2ZML7 162-304 None
J6F260 105-263 None
A0A7R8XAG2 550-706 None
A0A034V7J9 161-308 None
B0ETL3 280-447 None
A0A4Y7JJ41 3-146 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.